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Jon D. Plant, Moni B. Neradelik, Nayak L. Polissar, et al. Agreement between allergen-specific IgE assays and ensuing immunotherapy recommendations from four commercial laboratories in the USA. Vet Dermatol 2014;25:15-e16.
BACKGROUND: Canine allergen-specific IgE assays in the USA are not subjected to an independent laboratory reliability monitoring programme. HYPOTHESIS/OBJECTIVES: The aim of this study was to evaluate the agreement of diagnostic results and treatment recommendations of four serum IgE assays commercially available in the USA. METHODS: Replicate serum samples from 10 atopic dogs were submitted to each of four laboratories for allergen-specific IgE assays (ACTT®, VARL Liquid Gold, ALLERCEPT® and Greer® Aller-g-complete®). The interlaboratory agreement of standard, regional panels and ensuing treatment recommendations were analysed… (read more)
Jon D. Plant. An Update on the Diagnosis and Management of Canine Atopic Dermatitis. Intas Polivet 2013;14:241-244.
Canine atopic dermatitis (CAD) is a common, pruritic disease that negatively impacts dogs’ quality of life. The diagnosis is based on history, clinical findings and ruling out alternative diagnoses. Glucocorticoids and calcineurin inhibitors are effective for managing canine AD. Allergen specific immunotherapy (ASIT) is widely used to manage CAD in many countries, but requires allergy testing that may not be available or reliable. Region specific immunotherapy (RSIT), incorporating allergen mixtures standardized for specific geographic areas is a suitable alternative to ASIT when the reliability, availability and expense of allergy testing are limitations.
Jon D. Plant, Kinga Gortel , Marcel Kovalik, et al. Development and validation of the Canine Atopic Dermatitis Lesion Index, a scale for the rapid scoring of lesion severity in canine atopic dermatitis. Vet Dermatol 2012;23:515-e103.
BACKGROUND: The third iteration of the Canine Atopic Dermatitis Extent and Severity Index (CADESI-03) is the only tool rigorously validated for canine atopic dermatitis (CAD) lesion scoring. The CADESI-03 requires 248 evaluations, limiting its widespread use. HYPOTHESIS/OBJECTIVES: The goal of the study was to develop and validate a practical method of grading CAD lesions that requires scoring only the frequently affected body regions. METHODS: The Canine Atopic Dermatitis Lesion Index (CADLI) was… (read more)
Jon D. Plant, Elizabeth M. Lund and Mingyin Yang. A case–control study of the risk factors for canine juvenile-onset generalized demodicosis in the USA. Veterinary Dermatology, 22(1), 2011, Pages: 95–99.
Canine juvenile-onset generalized demodicosis (JOGD) is a common skin disorder suspected to be associated with multiple risk factors, including breed predispositions. These risk factors have not been well documented in a large population. A retrospective case–control study was conducted by searching the electronic medical records of 1,189,906 dogs examined at 600 hospitals during 2006 in order to assess the risk factors associated with JOGD in the USA. Multivariate analyses were conducted using logistic regression to estimate the relative risk with the odds ratio for variables hypothesized to influence the risk for canine demodicosis…(read more)
Jon D. Plant. Correlation of observed nocturnal pruritus and actigraphy in dogs. Veterinary Record 2008;162:19 624-625. (abstract not available).
Jon D. Plant, Jack N. Giovanini and Aurora Villarroel. Frequency of appropriate and inappropriate presentation and analysis methods of ordered categorical data in the veterinary dermatology literature from January 2003 to June 2006. Veterinary Dermatology, 18(4), 2007, Pages: 260–266.
Clinical outcomes that are difficult to measure directly are often graded with ordinal scales in the veterinary dermatology literature to approximate objective evaluation. Ordered categorical scales require statistical presentation and analysis methods consistent with the structure of the data. The objective of this study was to determine the frequency of inappropriate presentation and analysis methods of ordered categorical data in the recent veterinary dermatology literature. A total of 62 articles published between 1 January 2003 and… (read more)
Jon D. Plant. Repeatability and reproducibility of numerical rating scales and visual analogue scales for canine pruritus severity scoring. Veterinary Dermatology, 18(5), 2007, Pages: 294–300.
Although they are used frequently in veterinary dermatology, the reliability of canine pruritus severity scales has not been reported. The objective of this study was to evaluate the reliability of pruritus severity numerical rating scales (NRS) and pruritus severity visual analogue scales (VAS). Videos of 16 dogs were evaluated for pruritus severity by 24 observers utilizing three NRS and three VAS. Intraobserver repeatability and interobserver reproducibility were evaluated with Cohen's kappa and Kendall's rank correlation statistics, respectively. (read more)
Jon D. Plant, Wayne S. Rosenkrantz, Craig E. Griffin. Factors associated with and prevalence of high
The prevalence of cutaneous